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. 2022 Jul 8;23:180. doi: 10.1186/s12931-022-02105-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Determination of MMP-2 and MMP-9 levels in lung tissue of ILD patients and disease controls. A, B MMP-2 (A) and MMP-9 (B) protein levels in explant lung tissue samples from lower and upper lung aspects of patients with IPF-UIP and non-IPF-UIP pattern, and from tumor-free lung tissue of disease control patients. Data are presented as scatter plots with median values indicated as horizontal lines of n = 10–12 patients per group. *p < 0.05, ***p < 0.001 compared to disease control (Mann–Whitney U test)