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. 2022 Jul 8;21:128. doi: 10.1186/s12933-022-01563-z

Table 2.

Cox proportional hazard ratios (HR) for all-cause mortality

Categories Events (%) Model 1 Model 2 Model 3
HR (95% CI) P-value P for trend HR (95% CI) P-value P for trend HR (95% CI) P-value P for trend
Hospital death
 Continuous variable per 1 unit 1.29 (1.12–1.48) < 0.001 1.26 (1.09–1.46) 0.002 2.19 (1.59–3.03) < 0.001
 Quartilea 350 (11.57) < 0.001 0.004 < 0.001
  Q1 (N = 756) 57 (7.54) Ref. Ref. Ref.
  Q2 (N = 755) 85 (11.26) 1.57 (1.12–2.20) 0.008 1.57 (1.12–2.21) 0.009 1.70 (1.06–2.70) 0.027
  Q3 (N = 758) 102 (13.46) 1.73 (1.25–2.39) < 0.001 1.69 (1.22–2.35) 0.002 2.08 (1.29–3.33) 0.002
  Q4 (N = 757) 106 (14.00) 1.75 (1.27–2.42) < 0.001 1.69 (1.20–2.37) 0.003 2.80 (1.53–5.13) < 0.001
ICU death
 Continuous variable per 1 unit 1.31 (1.12–1.53) < 0.001 1.21 (1.02–1.43) 0.029 1.72 (1.18–2.52) 0.005
 Quartile 258 (8.53) 0.002 0.030 0.036
  Q1 (N = 756) 42 (5.56) Ref. Ref. Ref.
  Q2 (N = 755) 59 (7.81) 1.46 (0.98–2.17) 0.060 1.44 (0.96–2.15) 0.074 1.52 (0.88–2.64) 0.136
  Q3 (N = 758) 77 (10.16) 1.75 (1.20–2.54) 0.004 1.65 (1.13–2.42) 0.010 1.88 (1.09–3.24) 0.023
  Q4 (N = 757) 80 (10.57) 1.78 (1.22–2.58) 0.003 1.55 (1.04–2.29) 0.030 1.95 (0.96–3.99) 0.066

Model 1: unadjusted

Model 2: adjusted for age, sex, ethnicity, first care unit

Model 3: adjusted for age, sex, ethnicity, first care unit, SOFA score, LODS score, white blood cell, red blood cell, hemoglobin, serum sodium, serum potassium, total cholesterol, low-density lipoprotein, high-density lipoprotein, albumin, serum creatinine, coronary heart disease, heart failure, hypertension, dyslipidemia, diabetes, chronic obstructive pulmonary disease, respiratory failure, liver disease, chronic kidney disease, acute kidney injury, sepsis, cancer

aTyG index: Q1 (6.23–8.65), Q2 (8.65–9.08), Q3 (9.08–9.59), Q4 (9.59–12.43)