Table 1.

Demographic characteristics and mean symptom severity scores of study participants.

Characteristics	Healthy controls	Close contacts	Mild disease	Moderate disease
A. Bulk assays for ATAC-seq and RNA-seq
Number of subjects	7	7	8	7
Age Mean (range), years	39.7 (25–61)	42.9 (17–61)	33.0 (27–60)	34.0 (20–52)
Sex (male/female)	3/4	4/3	5/3	3/4
Max severity score (± SE)	N/A	9.9 ± 2.9	12.8 ± 1.9	33.6 ± 2.4

Characteristics	Healthy controls	Close contacts	Mild disease	Moderate disease
B. Single cell assays for ATAC-seq/RNA-seq
Number of subjects	5	3	5	5
Age Mean (range), years	45.2 (28–61)	53.2 (43–61)	35.6 (27–60)	37.7 (29–52)
Sex (male/female)	1/4	2/1	5/0	1/4
Max severity score (± SE)	N/A	3.3 ± 2.8	12.2 ± 2.8	36.0 ± 2.3