Table 1:
Consensus opinion recommendations for protocol monitoring of whole organ pancreas transplants.
| Static Metabolic Testing | ||||||
|---|---|---|---|---|---|---|
| Not monitored routinely |
≤ 1 month | Every 1-3 months |
Every 6 months |
Annually | Consensus Opinion | |
| Weight | 0 (0.0%) | 11 (45.8%) | 22 (91.7%) | 1 (4.2%) | 8 (33.3%) |
Suggested ≤ 1 month Strongly recommended: every 1-3 months |
| Fasting glucose | 0 (0.0%) | 14 (58.3%) | 23 (95.8%) | 2 (8.3%) | 2 (8.3%) |
Suggested ≤ 1 month Strongly recommended: every 1-3 months |
| HbA1c | 0 (0.0%) | 8 (33.3%) | 20 (83.3%) | 4 (16.7%) | 4 (16.6%) | Strongly recommended every 1-3 months |
| Fasting C-peptide | 2 (8.3%) | 10 (41.7%) | 15 (62.5%) | 3 (12.5%) | 5 (20.8%) | Recommended every 1-3 months |
| Random C-peptide | 18 (75%) | 3 (12.5%) | 3 (12.5%) | 1 (4.2%) | 3 (12.5%) | Not recommended routinely |
| Fasting insulin | 17 (70.8%) | 0 (0.0%) | 4 (16.7%) | 2 (8.3%) | 2 (8.3%) | Not recommended routinely |
| Dynamic Metabolic Testing | ||||||
| Oral Glucose Tolerance Test | 14 (58.3%) | 2 (8.3%) | 1 (4.2%) | 1 (4.2%) | 6 (25%) | Not recommended routinely |
| Mixed Meal/Stim Tests: (MMTT, AST, IVGTT) | 17 (70.8%) | 0 (0.0%) | 2 (8.3%) | 1 (4.2%) | 3 (12.5%) | Not recommended routinely |
| Clamp | 22 (91.7%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (4.2%) | Not recommended routinely |
| Continuous Glucose Monitoring | 18 (75%) | 1 (4.2%) | 0 (0.0%) | 0 (0.0%) | 2 (8.3%) | Not recommended routinely |
| Immunologic Testing | ||||||
| DSA's | 7 (29.2%) | 9 (37.5%) | 12 (50.0%) | 4 (16.7%) | 9 (37.5%) | Suggested every 1-3 months |
| Autoantibodies | 17 (70.8%) | 1 (4.2%) | 1 (4.2%) | 2 (8.3%) | 1 (4.2%) | Not recommended routinely |
| Pancreas Graft Protocol Biopsy | ||||||
| Type of pancreas transplant | Not monitored routinely | SPK | PAK | PTA | Consensus Opinion | |
| 19 (79.2%) | 2 (8.3%) | 5 (20.8%) | 5 (20.8%) | Not recommended routinely | ||