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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: J Allergy Clin Immunol. 2022 Jan 24;150(1):114–130. doi: 10.1016/j.jaci.2021.12.794

Fig 5. Effect of cutaneous co-delivery of hapten and NK1R antagonists on mouse skin DC.

Fig 5.

A) Populations of mouse skin DCs analyzed by FACS in skin-dLN. B) Quantification of percentages (left) and numbers (right) of skin DCs homing in skin-dLN of KikGR mice treated with MNAs. One experiment of 4. C) Transport of OVA•TR and IL-10 content in DCs mobilized to skin-dLN of IL-10-EGFP-reporter mice treated with MNAs. In (B and C) Numbers in dot plots are percentages of cells per quadrants. D and E) Numbers of skin DC expressing OVA•TR (D) or with IL-10 content (E), in skin-dLN of mice. One experiment of 3. F) Effect of LC depletion on the inhibition of CHS to OVA assessed by ear thickness. One experiment of 3. Four mice per experimental group. Means ± 1 SD were analyzed by 1-way ANOVA followed by comparison between all means by Student-Newman-Keuls test. *p < 0.01, ***p < 0.001, ****p < 0.0001. NS: not significant.