Table 2.

Brain Regions Showing Reward-Related Activity in Individuals With RNT Compared With HC Individuals

	Coordinates
Test Condition	x	y	z	Number of Voxels	Region	β (CI)	Cohen’s d
VH-RNT vs. HC
Gain	−19	−63	−31	1599	L cerebellum	−1.21 (−1.63 to −0.79)	−1.25
	−5	−3	11	327	Midbrain extending to the ventral tegmental area	−1.03 (−1.49 to −0.58)	−1.00
	−11	5	31	229	L anterior cingulate cortex	−1.19 (−1.60 to −0.79)	−1.28
	7	−53	−7	186	Mid cerebellum	−0.86 (−1.20 to −0.52)	−1.09
	37	9	35	183	R inferior frontal gyrus	−1.06 (−1.46 to −0.67)	−1.19
Loss	19	9	39	184	R superior frontal gyrus	−1.31 (−1.74 to −0.90)	−1.38
	−3	15	7	174	Basal ganglia/R anterior caudate/L anterior horn	−1.06 (−1.52 to −0.61)	−1.03
H-RNT vs. HC
Gain	−3	−83	−21	342	Mid cerebellum	−1.07 (−1.49 to −0.64)	−1.12
	21	−63	−31	312	R cerebellum	−0.96 (−1.31 to −0.61)	−1.21
Loss	19	11	39	384	R superior frontal gyrus	−1.43 (−1.89 to −0.98)	−1.41
	−21	−47	21	228	L inferior horn vicinity	−1.16 (−1.55 to −0.77)	−1.33
	15	33	1	172	R anterior caudate	−1.01 (−1.43 to −0.59)	−1.07

HC, healthy comparison; H-RNT, high RNT; L, left; R, right; RNT, repetitive negative thinking; VH-RNT, very high RNT.