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. 2022 Jun 27;13:890029. doi: 10.3389/fendo.2022.890029

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Copyright © 2022 Zhang, Xiao, Liu, He, Cui, Tang, Li and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prevalence of coronary heart disease (CHD) and stroke by quartiles of serum dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) in men and women. (A, B) Prevalence of CHD by DHEA (A) and by DHEAS (B). (C, D) Prevalence of stroke by DHEA (C) and by DHEAS (D). The figure shows that the percentages of men with CHD significantly decreased in accordance with increasing quartiles of serum DHEA and DHEAS (all p < 0.001). The prevalence of stroke significantly decreased in line with increasing quartiles of serum DHEA in women (p = 0.003) and DHEAS in men (p = 0.011).