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. 2022 Jun 27;13:890029. doi: 10.3389/fendo.2022.890029

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Copyright © 2022 Zhang, Xiao, Liu, He, Cui, Tang, Li and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Receiver operating characteristic (ROC) curve analysis of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) to recognize coronary heart disease (CHD) in men with type 2 diabetes mellitus. ROC curve analysis revealed that the areas under the curve (AUCs) for DHEA (A) and DHEAS (B) were 0.66 (95% CI = 0.60–0.72) and 0.64 (95% CI = 0.58–0.69), respectively. The optimal cutoff values, with the best trade-off between sensitivity and specificity, were 6.43 nmol/L for DHEA and 3.54 μmol/L for DHEAS.