Table 5.
Antibiotic Carbapenemase Gene |
CZA | C/T | FDC | ||||||
---|---|---|---|---|---|---|---|---|---|
S | I | R | S | I | R | S | I | R | |
N | N | N | N | N | N | N | N | N | |
(%) | (%) | (%) | (%) | (%) | (%) | (%) | (%) | (%) | |
CR Klebsiella (52): | 11 | - | 41 | 0 | 0 | 52 | 50 | 2 | 0 |
21 | - | 79 | 0.0 | 0.0 | 100 | 96 | 4 | 0.0 | |
- Carbapenemase genes negative (n=10) | 5 | - | 5 | 0 | 0 | 10 | 10 | 0 | 0 |
50 | - | 50 | 0.0 | 0.0 | 100 | 100 | 0.0 | 0.0 | |
- Carbapenemase genes positive (n=42) | 6 | - | 36 | 0 | 0 | 42 | 40 | 2 | 0 |
14.3 | - | 85.7 | 0.0 | 0.0 | 100 | 95.2 | 4.8 | 0.0 | |
● Class B MBL (blaNDM) positive (n=17) | 0 | - | 17 | 0 | 0 | 17 | 17 | 0 | 0 |
0.0 | - | 100 | 0.0 | 0.0 | 100 | 100 | 0.0 | 0.0 | |
● Class A (blaKPC) positive (n=6) | 2 | - | 4 | 0 | 0 | 6 | 6 | 0 | 0 |
33.3 | - | 66.7 | 0.0 | 0.0 | 100 | 100 | 0.0 | 0.0 | |
● Class D (blaOXA-48) positive (n=10) | 4 | - | 6 | 0 | 0 | 10 | 10 | 0 | 0 |
40 | - | 60 | 0.0 | 0.0 | 100 | 100 | 0.0 | 0.0 | |
● Both blaNDM+ OXA-48 positive (n=9) | 0 | - | 9 | 0 | 0 | 9 | 7 | 2 | 0 |
0.0 | - | 100 | 0.0 | 0.0 | 100 | 77.7 | 22.2 | 0.0 |
Abbreviations: CZA, ceftazidime–avibactam; C/T, ceftolozane–tazobactam; FDC, cefiderocol.