TABLE 1.

Bacillus Calmette–Guérin proteins overexpressed vs. mycobacterium Mtb proteins.

No.	BCG (Chicago)	TB (H37Rv)	NCBI accession no.	Protein	Rv name	Function
1	Up	Down	585892	L7/L12 50S ribosomal protein	Rv0652	Activates inflammatory pathway (TLR4, TNFa, IL-6 IL-1b) IFNg (Lee et al., 2014)
2	Up	Down	2127455	AhpC/TSA family	Rv2429	against oxidant and nitrozant reaction of macrophages (Alharbi et al., 2019)
3	Up	Mobility variant	1452900	S-adenosyl-methionine syntase	Rv1392	Produces the major methyl donor (Chiang et al., 1996)
4	Up	None	1817673	G6PD	Rv0407	Possible host switch to aerobic glycolysis (Stincone et al., 2015)
5	Up	None	2072672	SimilarProtects to Soj protein	Rv3213c	Mycobacterial proteasomal substrate, chromosome partitioning (Hu et al., 2018)
6	Up	Down	2104386	Neuraminidase?	Rv3463	Enhances bacterial phagolysosomal fusion in host (Park et al., 2019)
7	Up	Down	1781160	Contains pyridoxal phosphate attachment site	Rv3054c	Aminotransferase class II
8	Up	None	2143298	Arylsulphatase	Rv0663	Intermediate and lipid metabolism and respiration
9	Up	Mobility variant	1694860	Oxidoreductase aldo/keto family	Rv2971	Effector oxidative damage, NADPH cofactor (Picklo et al., 2001)
10	Up	Mobility variant	2808725	Oxidoreductase	Rv0068	Oxidoreductase, respiration intermediate metabolism