Table 1.
The immune subtype distribution in different histotypes of ovarian cancer [based on Webb et al. (37)].
| Histotype | Percentage of different tumor microenvironment type (%) | |||
|---|---|---|---|---|
| Type I: Adaptive immune resistance | Type II: Immunological ignorance | Type III: Intrinsic induction | Type IV: Tolerance | |
| TIL &PD-L1 (+) | TIL &PD-L1 (-) | TIL (-) & PD-L1 (+) | TIL (+) & PD-L1 (-) | |
| High grade serous cancer | 57.4 | 5.1 | 0 | 37.4 |
| Low grade serous cancer | 0 | 9.1 | 0 | 90.9 |
| Clear cell cancer | 16.2 | 30.2 | 0 | 53.5 |
| Endometrioid cancer | 22.4 | 14.4 | 1.6 | 61.6 |
| Mucinous cancer | 26.7 | 16.7 | 0 | 56.7 |
TILs, tumor-infiltrating lymphocytes; PD-L1, programmed death ligand 1.