TABLE 2.

Comparison of genotypes and allele distribution frequencies between the CC group and its subgroups with the healthy control group.

Genotype and allele	Control	Case	P	OR [95% CI]	Statistical model	P′	P′′	OR [95% CI]
	Controls (n= 495)	CC(n = 482)
AA	259 (52.3%)	235 (48.8%)			Dominant	0.2054	0.2095	0.829[0.620–1.108]
AG	189 (38.2%)	199 (41.3%)			Recessive	0.5305	0.5327	0.852[0.516–1.406]
GG	47 (9.49%)	48 (9.96%)	0.5322		Additive	0.2132	0.2088	0.868[0.696–1.084]
A	707 (71.4%)	669 (69.4%)
G	283 (28.6%)	295 (30.6%)	0.3290	0.908[0.747–1.102]
	Controls (n= 495)	SCC (n = 416)
AA	259 (52.3%)	204 (49.0%)			Dominant	0.2967	0.2968	0.851[0.628–1.152]
AG	189 (38.2%)	169 (40.6%)			Recessive	0.4040	0.4110	0.801[0.476–1.348]
GG	47 (9.49%)	43 (10.3%)	0.6110		Additive	0.2443	0.2437	0.872[0.692–1.098]
A	707 (71.4%)	577 (69.4%)
G	283 (28.6%)	255 (30.6%)	0.3362	1.104[0.902–1.351]
	Controls (n= 495)	AUC(n = 36)
AA	259 (52.3%)	16 (44.4%)			Dominant	0.2542	0.2631	0.659[0.321–1.350]
AG	189 (38.2%)	16 (44.4%)			Recessive	0.5203	0.5204	0.680[0.209–2.207]
GG	47 (9.49%)	4 (11.1%)	0.6589		Additive	0.2441	0.2462	0.727[0.425–1.243]
A	707 (71.4%)	48 (66.7%)
G	283 (28.6%)	24 (33.3%)	0.3909	0.801[0.481–1.332]

CC, cervical cancer; SCC, squamous carcinoma of cervical; AUC, adenocarcinoma of the uterine cervical; OR, odds ratio; CI, confidence interval.

P: p-value (control vs. CC; control vs. SCC; control vs. AUC ); p-values <0.05 are shown in bold.

P’: age was adjusted.

P”: the p-value was calculated using 10,000 permutations for each model to correct the multiple tests.