Table 1.
Clinical characteristics of dual-diagnosis subjects compared to IBD alone and to EoE alone:
| EoE and IBD (n = 67) | IBD alone (n = 150) | P | EoE alone (n = 150) | P | |
|---|---|---|---|---|---|
| Age in years at diagnosis, n (%) | |||||
| IBD | 11.3 ± 4.3 | 11.6 ± 4.0 | 0.50 | ||
| EoE | 12.2 ± 4.7 | 7.3 ± 4.9 | <0.001 | ||
|
| |||||
| Male, n (%) | 56 (84) | 83 (55) | <0.001 | 123 (82) | 0.85 |
|
| |||||
| Race/Ethnicity, n (%) | |||||
| White | 54 (81) | 107 (71) | 0.18 | 114 (76) | 0.49 |
| Black | 5 (8) | 17 (11) | 0.47 | 21 (14) | 0.26 |
| Asian | 0 (0) | 3 (2) | 0.55 | 1 (1) | 1.00 |
| Latino | 2 (3) | 1 (1) | 0.23 | 5 (3) | 1.00 |
| Indian | 1 (2) | 6 (4) | 0.68 | 0 (0) | 0.31 |
|
| |||||
| Atopy, n (%) | |||||
| Asthma | 18 (27) | 27 (18) | 0.15 | 96 (64) | <0.001 |
| Eczema | 6 (9) | 26 (17) | 0.15 | 57 (38) | <0.001 |
| Allergic rhinitis | 24 (36) | 51 (34) | 0.88 | 129 (86) | <0.001 |
| IgE-mediated food allergy | 24 (36) | 10 (7) | <0.001 | 91 (61) | <0.001 |
|
| |||||
| IBD classification, n (%) | |||||
| Crohn’s disease | 45 (67) | 93 (62) | 0.54 | ||
| Ulcerative colitis | 17 (25) | 34 (22) | 0.73 | ||
| Indeterminate IBD | 5 (6) | 23 (15) | 0.13 | ||
| VEO-IBD | 13 (19) | 20 (13) | 0.31 | ||
IBD = inflammatory bowel disease; EoE = eosinophilic esophagitis; VEO-IBD = very early onset inflammatory bowel disease