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. Author manuscript; available in PMC: 2022 Jul 11.
Published in final edited form as: J Pediatr Gastroenterol Nutr. 2021 Mar 1;72(3):398–403. doi: 10.1097/MPG.0000000000003002

Table 3.

Inflammatory bowel disease medications used in dual-diagnosis subjects who were diagnosed with inflammatory bowel disease first and in subjects with inflammatory bowel disease alone

Medication Dual IBD first
n=32 [n(%)]
IBD
n=150 [n(%)]
RR 95% CI
Lower Upper
5-ASA 23 (72) 117 (78) 0.746 0.361 1.542
Methotrexate 7 (22) 50 (33) 0.589 0.263 1.318
Thiopurine 6 (19) 24 (16) 1.188 0.514 2.748
Anti-TNF 12 (38) 101 (67) 0.314 0.159 0.619
Vedolizumab 1 (3) 11 (7) 0.433 0.062 3.033
Ustekinumab 1 (3) 4 (3) 1.158 0.177 7.571
Tacrolimus 1 (3) 1 (0.01) 3.538 0.690 18.146

IBD medications and weighted relative risk of developing eosinophilic esophagitis. 5-ASA = 5-aminosalicylate, CI = confidence interval, IBD = inflammatory bowel disease, RR = relative risk; TNF = tumor necrosis factor.