Figure 2.

Design of promising PBM therapy^7,94 to improve the anti-inflammatory and osteogenic capacity of bone marrow-derived multipotent mesenchymal cells (MSCs). The homogeneity of flat-top hand-piece irradiation (a) improves the PBM-t consistency, (b) in vitro irradiation of MSCs through 1 W and 60 J/cm² irradiated in continuous-wave mode on an area of about 1 cm² for 60 s with an 808-nm diode laser light (see Table 1), and the major cell target and (c) cellular pathway, secretome and cell agenda stimulated by the therapy (for further information see Tables 1 and 2), (figure created with BioRender.com).