Table 1.

The Composition of the Experimental Runs According to the D-Optimal Statistical Design and Their Responses

Runs	A Oils (%)	B S/Cos (%)	C Water (%)	Y1* GS (nm)	Y2* PDI	Y3* %T	Y4* Viscosity (cp)
1	28.49	53.20	18.31	26.42±0.37	0.42±0.08	98.76±0.08	342.83±3.55
2	24.36	51.23	24.41	29.52±0.10	0.41±0.02	86.12±0.72	495.83±5.78
3	23.20	62.03	14.77	25.87±1.31	0.43±0.07	98.36±0.57	285.50±2.04
4	31.38	58.62	10.00	34.12±1.42	0.35±0.05	92.56±1.54	320.20±3.44
5	40.55	49.45	10.00	73.01±3.03	0.59±0.07	75.25±0.51	336.30±2.46
6	45.00	45.00	10.00	68.64±2.18	0.29±0.05	61.93±4.28	324.17±5.92
7	38.46	45.00	16.54	58.22±3.58	0.42±0.06	79.05±2.32	354.77±6.23
8	45.00	45.00	10.00	63.96±3.10	0.25±0.02	65.21±3.23	333.03±2.59
9	20.00	57.26	22.74	18.75±1.86	0.68±0.02	99.11±0.30	433.90±1.47
10	20.00	70.00	10.00	151.00±28.82	0.58±0.01	72.03±0.65	312.40±5.20
11	20.00	70.00	10.00	147.00±33.93	0.56±0.01	68.85±0.06	340.87±2.95
12	29.44	45.56	25.00	29.89±1.78	0.84±0.01	85.29±2.10	418.97±2.50
13	29.44	45.56	25.00	28.37±2.26	0.80±0.01	80.86±1.82	456.63±3.43
14	20.00	57.26	22.74	15.20±1.18	0.65±0.00	99.63±0.60	470.23±19.20
15	38.46	45.00	16.54	46.15±3.02	0.47±0.04	87.39±2.56	321.77±4.46
16	35.32	51.81	12.87	59.49±3.37	0.31±0.03	77.85±1.35	382.80±3.46

Notes: *All values are represented as mean ± standard deviation of three measurements for three different batches (n = 3). Collagen (10 mg) was incorporated in all formulations with a final concentration of 1% w/w.

Abbreviations: S/Cos, surfactant/cosurfactant; GS, globule size; PDI, polydispersity index; %T, percent transmittance.