Table 3. Demographic and clinical characteristics of the infection-uncontrolled and controlled groups.
Infection-uncontrolled ( n = 5) | Controlled ( n = 8) | p -Value | |||
---|---|---|---|---|---|
Patients' background | |||||
Age (y) | 80.4 (72–90) | 70.4 (60–87) | 0.06 | ||
Sex | Male | 5 | 6 | 0.36 | |
Female | 0 | 2 | |||
Immunocompromised status (diabetes mellitus, steroid use, etc.) | Yes | 5 | 5 | 0.20 | |
No | 0 | 3 | |||
Symptoms | |||||
Period from onset to the start of treatment (days) | 192.0 (25–490) | 81.8 (18–157) | 0.29 | ||
Severe pain (opioid use) | Yes | 4 | 5 | 0.49 | |
No | 1 | 3 | |||
Fever (>38°C) | Yes | 1 | 1 | 0.64 | |
No | 4 | 7 | |||
Refractory external otitis | Yes | 4 | 8 | 0.38 | |
No | 1 | 0 | |||
Cranial nerve palsy | Yes | 3 | 2 | 0.25 | |
(Solitary VII palsy) | (1) | (1) | |||
(Other nerve palsy [IX, X, XII]) | (2) | (1) | |||
No | 2 | 6 | |||
Pretreatment laboratory data | |||||
HbA1c (%) | 6.9 (6.1–8.0) | 7.3 (5.2–12.2) | 0.74 | ||
ESR (mm/h) | 105.0 (67–143) | 85.0 (58–111) | 0.39 | ||
CRP (mg/dL) | 6.2 (0.35–12.6) | 7.0 (1.16–30.35) | 0.87 | ||
Bacteria | Pseudomonas aeruginosa | Yes | 4 | 3 | 0.18 |
No | 1 | 5 | |||
Fungi | Yes | 2 | 2 | 0.51 | |
No | 3 | 6 | |||
Treatment | |||||
Intravenous antibiotic administration | Yes | 5 | 7 | 0.62 | |
No | 0 | 1 | |||
Surgery | Yes | 0 | 3 | 0.20 | |
No | 5 | 5 | |||
Hyperbaric oxygen therapy | Yes | 2 | 5 | 0.41 | |
No | 3 | 3 | |||
Infection control team intervention | Yes | 3 | 6 | 0.51 | |
No | 2 | 2 |
Abbreviations: CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; Hb, hemoglobin.