Figure 3.

NDEx and SPP integration democratizes access to the T1D CIC transcriptional regulatory networks

(A) Detail of NDEx ET1DRE network.

(B) Detail of SPP transcriptomic (upper panel) and ChIP-Seq Regulation Reports of ET1DREs to show evidence for signaling nodes that regulate their expression.

(C) Detail of NDEx ET1DRE node network. In NDEx networks, transcript (A) and node class edges (B) are color coded as follows: receptors (orange red), enzymes (blue), transcription factors (green), ion channels (mustard), and co-nodes (gray). In both NDEx network types, the network info tab (upper inset) contains a description of the resoure, while clicking on a transcript (A) or node (B) shows the node/ege window (lower inset) containing links to selected contextual web research resources.