Table 1.
Links to NDEx versions of transcriptional networks developed for this study
| Type | Name | Description |
|---|---|---|
| C-FLEE | p < 0.05 ET1DREs | Transcripts that are preferentially repressed in T1D CICs |
| p < 0.05 ET1DIEs | Transcripts that are preferentially induced in T1D CICs | |
| Top-ranked ET1DREs | Top 20 ET1DREs ranked by enrichment p value (Figure 1E left panel) | |
| Top-ranked ET1DIEs | Top 20 ET1DIEs ranked by enrichment p value (Figure 1E right panel) | |
| HCT intersection | p < 0.05 ET1DRE nodes | Signaling pathway nodes predicted to regulate expression of ET1DREs at p < 0.05 |
| p < 0.05 ET1DIE nodes | Signaling pathway nodes predicted to regulate expression of ET1DIEs at p < 0.05 | |
| Top ET1DRE nodes | Top 20 ET1DRE nodes ranked by intersection p value (Figure 2G, upper panel) | |
| Top ET1DIE nodes | Top 20 ET1DIE nodes ranked by intersection p value (Figure 2G, lower panel) | |
| Expt 6607 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6608 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6609 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D monocytes | |
| Expt 6610 induced | repressed | Nodes predicted to regulate genes differentially expressed in mild T1D CD14+ monocytes | |
| Expt 6611 induced | repressed | Nodes predicted to regulate genes differentially expressed in severe T1D CD14+ monocytes | |
| Expt 6612 induced | repressed | Nodes predicted to regulate genes differentially expressed in mild T1D CD14+ monocytes | |
| Expt 6613 induced | repressed | Nodes predicted to regulate genes differentially expressed in severe T1D CD14+ monocytes | |
| Expt 6614 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D whole blood | |
| Expt 6615 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D whole blood | |
| Expt 6623 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6627 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6628 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6629 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6630 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6631 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6632 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6633 repressed | Nodes predicted to regulate genes repressed in T1D CD14+ monocytes | |
| Expt 6634 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D whole blood | |
| Expt 6642 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D CD34+ HSCs | |
| Expt 6650 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D CD3+ T cells | |
| Expt 6651 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D neutrophils | |
| Expt 6686 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D neutrophils | |
| Expt 6687 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D neutrophils | |
| Expt 6655 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D monocyte-derived DCs | |
| Expt 6656 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs | |
| Expt 6657 induced | repressed | Nodes predicted to regulate genes differentially expressed in T1D PBMCs |
No nodes were identified that had significant HCT intersections with experiment 6633 induced genes.