Table 3.
Anthropometric and radiologic parameters categorized by ACS status
| ACS (n = 35) | Nonfunctional adenoma (n = 114) |
P value | |
|---|---|---|---|
| Age, years (SD) | 60.1 (12.0) | 57.3 (10.5) | 0.16 |
| Women, % | 82% | 76% | 0.23 |
| BMI, kg/m2, mean (SD) | 30.6 (4.4) | 28.3 (4.0) | 0.16 |
| Hypertension, % | 61 | 53 | 0.40 |
| Dysglycemia, % | 28 | 26 | 0.87 |
| Dyslipidemia, % | 60 | 53 | 0.37 |
| Adenoma diameter, mm (SD) | 28.6 (8.1) | 17.6 (6.3) | <0.001 |
| Adenoma volume, cm3 (SD) | 10.7 (9.7) | 2.8 (3.9) | <0.001 |
| Contralateral adrenal gland volume, cm3 (SD) | 1.9 (0.6) | 2.9 (1.1) | <0.001 |
| Adenoma volume/ Contralateral adrenal volume ratio (SD) | 7.3 (10.6) | 1.3 (3.3) | <0.001 |
| DST (ug/dL, mean, SD) | 4.7 (4.9) | 0.9 (0.3) | <0.001 |
| ACTH, pg/mL, mean (SD) | 9.5 (5.7) | 17.2 (8.3) | <0.001 |
Values are expressed as n, total number (%), or mean (SD) where appropriate.
Abbreviations: ACS, possible autonomous cortisol secretion; DST, 1 mg overnight dexamethasone suppression test.