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. 2022 Jan 10;107(5):e1946–e1953. doi: 10.1210/clinem/dgac005

Table 4.

Area under ROC curves and estimate sensitivity and specificity of unadjusted and adjusted predictive models for possible autonomous cortisol secretion (ACS)

Unadjusted Adjusted by laterality Adjusted by laterality, age, and sex
Odd ratio (95% CI) 1.40 (1.18-1.65) 1.40 (1.18-1.66) 1.41 (1.19-1.68)
AUC (95% CI) 0.91 (0.86-0.96) 0.89 (0.84-0.95) 0.88 (0.81-0.95)
Sensitivity and specificity of
AV/CV ratio ≥ 1
S = 97
E = 70
S = 94
E = 64
S = 91
E = 72
Sensitivity and specificity of
AV/CV ratio ≥ 3
S = 62
E = 95
S = 62
E = 93
S = 59
E = 93

Abbreviations: ACS, possible autonomous cortisol secretion; AUC, area under the curve; AV/CV, adrenal volume/contralateral adrenal volume; E, specificity; S, sensitivity.