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Frequency of EBV Infection in Breast Cancer Patients and Controls
| Control group No. (%) |
BC patients No. (%) |
P-value | OR (95% CI) | |
|---|---|---|---|---|
| Anti- VCA IgG (n) | 220 | 142 | ||
| Seronegative | 40 (18.2) | 22 (15.5) | Reference | |
| Seropositive | 180 (81.8) | 120 (84.5) | 0.507 | 1.2 (0.68-2.14) |
| EBNA-1 gene (n) | 180 | 120 | ||
| Negative | 142 (78.9) | 66 (55) | Reference | |
| Positive | 38 (21.1) | 54 (45) | <0.001 | 3.05 (1.84-5.07) |
EBV, Epstein-Barr virus; VCA, Viral capsid antigen; EBNA, Epstein Barr virus nuclear antigen; BC, breast cancer.
