Table 3.
EBV Typing in Breast Cancer Patients and Controls
| EBV types | Number (%) | P- value | OR (95%CI) | |
|---|---|---|---|---|
| Control group (n=38) |
BC patints (n=54) |
|||
| A/B genotypes | ||||
| Successful typing | 36 (94.7) | 52 (96.3) | ||
| A-genotype | 33 (91.7) | 47 (90.4) | Reference | |
| B-genotype | 3 (8.3) | 5 (9.6) | 0.837 | 1.102 (0.43-2.78) |
| C/D subtypes | ||||
| Successful typing | 34 (89.5) | 45 (83.3) | ||
| C-subtype | 12 (35.3) | 2 (4.4) | Reference | |
| D-subtype | 22 (64.7) | 43 (95.6) | 0.002 | 11.7 (2.4-57.1) |
| F/f variants | - | |||
| Successful typing | 36 (94.7) | 48 (88.9) | ||
| F-variant | 36 (100) | 48 (100) | ||
| f-prototype | 0 | 0 | ||
| Combined types of EBV | ||||
| Successful typinga | 32 (84.2) | 39 (72.2) | ||
| ACF | 9 (28.1) | 1 (2.6) | Reference | |
| ADF | 20 (62.5) | 33 (84.6) | 0.005 | 4.92 (1.61-14.99) |
| BDF | 2 (6.2) | 4 (10.3) | 0.024 | 5.54 (1.25-24.41) |
| BCF | 1 (3.1) | 1 (2.6) | 0.217 | 3.62 (0.47-27.55) |
EBV, Epstein-Barr virus; VCA, Viral capsid antigen; EBNA, Epstein Barr virus nuclear antigen; NA, not amplified gene; BC, breast cancer; a, Combined types of EBV were calculated among 39 cases and 32 controls who were successfully typed for all 3 investigated regions