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. 2022 Jul 11;205:105381. doi: 10.1016/j.antiviral.2022.105381

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Fig. 5 — Analysis ofJMX0286, JMX0301,JMX0941and ML188binding to recombinant SARS-CoV-2 3CLpro: Surface plasmon resonance (SPR). Dose response curve upon titrating 100 μM–0.164 μM for JMX0286 (A), JMX0301 (B) and JMX0941 (C) and ML188 (D) against immobilized 3CLpro. Steady-state affinity model to determine binding affinity (K_D) values at equilibrium (E).