Table 1.
EC50 of Niclosamide derivatives against SARS-CoV-2.
| Comp Serial# | Comp ID | EC50 (μM) | CC50 (μM) |
|---|---|---|---|
| 1 | JMX0207 | 1.222 | 13.17 |
| 2 | JMX0281 | 2.078 | 8.32 |
| 3 | JMX0285 | 3.031 | 6.13 |
| 4 | JMX0286 | 2.251 | 3.78 |
| 5 | JMX0308 | 0.8065 | 1.80 |
| 6 | JMX0310 | 2.414 | 10.06 |
| 7 | JMX0312 | 1.129 | 1.97 |
| 8 | JMX0317 | 4.025 | 11.70 |
| 9 | JMX0321 | 1.186 | 3.76 |
| 10 | JMX0325 | 0.1228 | 1.81 |
| 11 | JMX0330 | 0.4981 | 10.15 |
| 12 | JMX0510–2 | 4.88 | 11.50 |
| 13 | JMX0670 | 3.202 | 9.17 |
| 14 | JMX0671 | 1.563 | 8.03 |
| 15 | JMX0672 | 1.921 | 8.34 |
| 16 | JMX0673 | 1.743 | 5.20 |
| 17 | JMX0674 | 9.752 | >10 |
| 18 | JMX0679 | 2.514 | 7.14 |
| 19 | JMX0680 | 4.566 | 10.10 |
| 20 | JMX0681 | 9.753 | >10 |
| 21 | JMX0682 | 1.568 | 6.48 |
| 22 | JMX0887 | 0.9203 | 4.18 |
| 23 | JMX0895 | 0.665 | 4.57 |
| 24 | JMX0929 | 2.425 | 5.06 |
| 25 | JMX0936 | 2.214 | 3.74 |
| 26 | JMX0940 | 1.216 | 7.72 |
| 27 | JMX0941 | 1.745 | 4.75 |
| 28 | JMX0942 | 2.891 | 7.20 |