KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Antibodies | ||
| Rabbit monoclonal anti-DYKDDDDK tag | Cell Signaling Technologies | Cat#D6W5B; RRID:AB_2572291 |
| Alexa Fluor 647-conjugated goat anti-rabbit secondary | Abcam | Cat#ab150079; RRID:AB_2722623 |
| Biological Samples | ||
| DM1 frozen post-mortem frontal cortex samples | Stanford University, The Research Resource Network Japan, University of Rochester Medical Center | N/A |
| Unaffected frozen post-mortem frontal cortex samples | NIH Biobank | N/A |
| Critical Commercial Assays | ||
| Direct-zol RNA Miniprep kit | Zymo Research | Cat#R2052 |
| NEBNext Ultra II Directional RNA Library kit | New England Biolabs | Cat#E7765S |
| Qubit dsDNA BR Assay Kit | ThermoFischer | Cat#Q32850 |
| Animal Tissue DNA Isolation Kit | Bionano Genomics | Cat#80002 |
| DLS DNA Labeling Kit | Bionano Genomics | Cat#80005 |
| Saphyr Chip G1.2 | Bionano Genomics | Cat#20319 |
| In-Fusion HD Cloning Plus | Clontech | Cat#638911 |
| TransIT-LT1 Transfection Reagent | Mirus Bio | Cat#MIR2306 |
| Deposited Data | ||
| Raw and analyzed data (both) | This paper | GEO: GSE157428 |
| Experimental Models: Cell Lines | ||
| Mouse Neuro2A Cells | Olmsted et al., 1970 | ATCC #CCL-131; RRID:CVCL_0470 |
| Oligonucleotides | ||
| See Table S7. | This paper | N/A |
| Recombinant DNA | ||
| Plasmid: pEGFP-C1 | Clontech | Cat#6084-1 |
| Plasmid: pcDNA3.1 | Invitrogen | CAT#V790-20 |
| Plasmid: pcDNA3.1-BicD2-KIF1Balpha | This paper | N/A |
| Plasmid: pcDNA3.1-V5-His-TOPO | Invitrogen | Cat#K4800-01 |
| Plasmid: FLAG-BicD2-KIF5A | This paper | N/A |
| Plasmid: FP-GRIP1-KBD +exon 21 | This paper | N/A |
| Plasmid: FP-GRIP1-KBD −exon 21 | This paper | N/A |
| Plasmid: BicD2-FKBP | Gift from Gary Banker, Bentley and Banker, 2015 | N/A |
| Software and Algorithms | ||
| FASTQC | Andrews, 2010 | https://www.bioinformatics.babraham.ac.uk/projects/fastqc/ |
| STAR | Dobin et al., 2013 | https://github.com/alexdobin/STAR |
| Kallisto | Bray et al., 2016 | https://pachterlab.github.io/kallisto/about |
| Sleuth | Pimentel et al., 2017 | https://pachterlab.github.io/sleuth/about |
| MISO | Katz et al., 2010 | https://miso.readthedocs.io/en/fastmiso/ |
| Pymc3 | Salvatier et al., 2016 | https://docs.pymc.io/ |
| Revigo | Supek et al., 2011 | http://revigo.irb.hr/ |
| SignalP | Nielsen et al., 1997 | http://www.cbs.dtu.dk/services/SignalP/ |
| ImageJ/Fiji | Schindelin et al., 2012 | https://imagej.net/Fiji |