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. 2022 Jul 8;37(1):1870–1883. doi: 10.1080/14756366.2022.2096020

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Scheme 1. — Synthesis of 1–4, 5A–E, 6A–E(a–c) and 7A–E(a–c). Reagents and conditions: (a) ClCH₂COOH, NaOH (aq), reflux, 2 h; (b) 30% H₂O₂, AcOH, rt, 3 h; (c) fuming HNO₃, 100 °C, 8 h; (d) corresponding diol, THF, 30% NaOH, 0 °C, 1 h; (e) corresponding anhydrides, TEA, DMAP, DCM, rt, 2 h; (f) DMAP, EDCI, rt, 4 h.