Pt-DMSO adducts identified in the ESI+ mass spectra of carboplatin and oxaliplatin after 24 h of incubation in DMSO/water (1 : 10).
| Molecular species | Formula | Observed massa | Theoretical mass | Error (ppm) |
|---|---|---|---|---|
| Carboplatin | ||||
| [Pt(NH3)2(CBDCA)(DMSO) + H]+ | C8H19N2O5PtS | 450.0664 | 450.0657 | 1.5 |
| [Pt(NH3)2(CBDCA)(DMSO) + Na]+ | C8H18N2O5PtSNa | 472.0483 | 472.0476 | 1.5 |
| [Pt(NH3)(DMSO)(CBDCA) + H]+ | C8H16NO5PtS | 433.0393 | 433.0391 | 0.5 |
| [Pt(NH3)(DMSO)(CBDCA) + Na]+ | C8H15NO5PtSNa | 455.0218 | 455.0211 | 1.1 |
| [Pt2(NH3)3(DMSO)(CBDCA)2 + H]+ | C14H28N3O9Pt2S | 804.0851 | 804.0836 | 1.8 |
| [Pt2(NH3)3(DMSO)(CBDCA)2 + Na]+ | C14H27N3O9Pt2SNa | 826.0672 | 826.0656 | 1.9 |
| Oxaliplatin | ||||
| [Pt(DACH)(OH)(DMSO)]+ | C8H21N2O2PtS | 404.0972 | 404.0966 | 1.4 |
| [Pt(DACH)(Ox)(DMSO) + H]+ | C10H21N2O5PtS | 476.0817 | 476.0813 | 0.9 |
| [Pt(DACH)(Ox)(DMSO) + Na]+ | C10H20N2O5PtSNa | 498.0635 | 498.0633 | 0.6 |
| [Pt(DACH)(Ox)(DMSO) + K]+ | C10H20N2O5PtSK | 514.0373 | 514.0372 | 0.5 |
a
Observed/theoretical masses are given for the monoisotopic peaks.