Table 4.

Sub-papillary and Remote LV Strain in Relation to Mitral Apparatus Remodeling

4a.
	Sub-papillary Radial Strain Quartiles
	1 (≥74%)	2 (51–73%)	3 (23–50%)	4 (<23%)	p
Mitral Annular Diameter (cm)	29.7±3.7	32.8±5.2	33.0±4.4	34.0±4.9	<0.01
Mitral Leaflet Tenting Height (cm)	7.3±1.8	7.1±2.8	9.1±2.3	11.2±3.1	<0.001
Mitral Valve Tenting Area (cm2)	1.14±0.39	1.32±0.83	1.73±0.49	2.47±1.00	<0.001
Interpapillary Fractional Shortening (%)	61.1±10.5	53.7±9.2	43.2±10.6	27.3±10.1	<0.001
	Non-papillary Radial Strain Quartiles
	1 (≥69%)	2 (49–68%)	3 (31–49%)	4 (<31%)	p
Mitral Annular Diameter (cm)	30.1±3.2	32.6±6.1	33.1±4.1	33.3±4.7	0.02
Mitral Leaflet Tenting Height (cm)	6.9±2.1	8.1±2.2	8.6±23.0	10.5±3.0	<0.001
Mitral Valve Tenting Area (cm2)	1.08±0.41	1.40±0.44	1.74±0.88	2.24±0.93	<0.001
Interpapillary Fractional Shortening (%)	59.9±11.5	51.9±11.7	46.7±11.9	30.8±11.3	<0.001

4b.
	Region	Multivariable β	95% CI	p
Mitral Annular Diameter (cm)	Sub-papillary radial strain	−0.06	[−0.11, −0.01]	0.02
	Non-papillary radial strain	0.01	[−0.04, 0.06]	0.87
Mitral Leaflet Tenting Height (cm)	Sub-papillary radial strain	−0.04	[−0.07, −0.02]	0.001
	Non-papillary radial strain	−0.01	[−0.04, 0.02]	0.49
Mitral Valve Tenting Area (cm2)	Sub-papillary radial strain	−0.01	[−0.02, −0.01]	0.001
	Non-papillary radial strain	−0.006	[−0.013, 0.002]	0.14
Interpapillary Fractional Shortening (%)	Sub-papillary radial strain	0.36	[0.26–0.46]	<0.001
	Non-papillary radial strain	0.07	[−0.05, 0.17]	0.22

Analysis encompassed patients with inducible perfusion defects on stress CMR and minimal infarction (≤ 5% LV myocardium, non-transmural) on LGE-CMR, with and without ≥moderate FMR, matched on ischemia extent and distribution (nested case:control cohort, n=111). All multivariable models (4b) include only the variables displayed – sub-papillary and non-papillary radial strain for each respective model.