Table 5.

Sub-papillary Strain and Mitral Apparatus Remodeling in Relation to ≥ Moderate Functional Mitral Regurgitation

5a.
Variable	Univariable Odds Ratio	95% CI	P	Multivariable Odds Ratio	95% CI	P
Sub-papillary radial strain (per 5% decrement)	1.15	1.07–1.24	<0.001	1.13	1.02–1.25	0.02
Mitral tenting area (per 10 mm2 increment)	1.06	1.03–1.10	<0.001	1.05	1.00–1.10	0.04
LV End-Systolic Volume (per 10ml increment)	1.06	1.03–1.10	<0.001	0.98	0.91–1.04	0.45

5b.
Variable	Univariable Odds Ratio	95% CI	p	Multivariable Odds Ratio	95% CI	p
Sub-papillary radial strain (per 5% decrement)	1.15	1.07–1.24	<0.001	1.22	1.02–1.47	0.03
Mitral tenting area (per 10 mm2 increment)	1.06	1.03–1.10	<0.001	1.16	1.02–1.32	0.02
LV Sphericity index (per 10% increment)	2.32	1.38–3.91	<0.001	2.19	1.06–14.50	0.03

Analysis encompassed patients with inducible perfusion defects on stress CMR and minimal infarction (≤ 5% LV myocardium, non-transmural) on LGE-CMR, with and without ≥moderate FMR, matched on ischemia extent and distribution (nested case:control cohort, n=111). Each multivariable model includes only the variables displayed.