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. 2022 Jun 30:eabl9943. doi: 10.1126/sciimmunol.abl9943

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Fig. 4. — Three antibody cocktail activates potent effector function responses in vitro. (A) Phagocytosis of Trimer-coated beads opsonized with single IMM antibodies and two antibody (IMM20184/20253) and three-antibody (IMM190/184/253) combinations . Denoted points are means of three replicates. Error bars denote SD. (B) Deposition of classical complement component C4 on IMM antibodies bound to Trimer-coated surface. Denoted points are means of four replicates. Error bars denote SD. (C) Activation of antibody-mediated cellular cytotoxicity (ADCC) by IMM antibodies and two antibody (IMM20184/20253) and three-antibody (IMM190/184/253) combinations bound to S-expressing cells. Denoted points are mean; error bars are SEM.