Table 3. Neutralization potency of the IMM-BCP-01 cocktail (IMM20184/190/253 antibody combination) against various pseudovirus Spike variants.
Isolate | IC50 (nM) |
REF (WA1/2020) | 1.0 |
BavPat (D614G) | 0.6 |
Alpha | 3.0 |
Beta | 13.5 |
Gamma | 24.8 |
B.1.617 (L452/E484Q) | 1.0 |
Delta | 0.4 |
Delta plus | 3.0 |
Epsilon | 0.6 |
Kappa (complete sequence) | 2.7 |
Lambda | 0.4 |
Mu | 9.1 |
Zeta | 1.53 |
Abbreviations: IC50 = half maximal inhibitory concentration; REF = reference.