Fig 7. dAP-rate homeostasis enhances context specificity.

A) Sketch of subpopulations of excitatory neurons representing the elements of the two sequences {F, D, B} and {A, D, B}, depicted by light and dark blue colors, respectively. Before learning, the connections between the subpopulations are immature (gray lines). Hence, for each element presentation, all neurons in the respective subpopulations fire (filled circles).B) Hebbian plasticity drives the formation of mature connections between subpopulations representing successive sequence elements (colored lines), and leads to sparse firing. The sets of neurons contributing to the two sequences partly overlap. C) Incorporating dAP-rate homeostasis reduces this overlap in the activation patterns.