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. 2022 Jul 7;17:2979–2993. doi: 10.2147/IJN.S358138

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© 2022 Du et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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In vivo anticancer study of HMMD@PG +L on 4T1-tumor-bearing mice based on intravenous administration. (I) PBS (control group), (II) DOX, (III) HMMD, (IV) HMMD@PG, (V) HMMD@PG + L. (A) Body weight, (B) tumor volume, (C) relative tumor weight and (D) tumor tissue images of 4T1-tumor-bearing mice with different treatments over 14 days. (E) H&E staining images of the dissected tumor tissues and (F) organs after 14 days of treatment. Scale bar: 50 µm. n = 5, *p < 0.05, **p < 0.01, ****p < 0.0001.

Abbreviation: L, laser.