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Maternal HDM exposure increased offspring airway sensory innervation. (A) Substance P–positive epithelial nerves in optically cleared airways (top) and three-dimensional computer models for quantification of nerve morphology (bottom). (B and C) Maternal HDM exposure increased offspring airway substance P–positive nerve length (B) and branching (C). Nerve length and branch points did not increase further with offspring HDM exposure. *P < 0.05.
