Table 1.

Contraindications for the use of P2Y12 receptor inhibitors in patients with acute coronary syndrome.

Contraindication	Clopidogrel	Prasugrel	Ticagrelor	Cangrelor
Hypersensitivity to the P2Y12 receptor inhibitor	X	X	X	X
Active bleeding	X	X	X	X
Severe liver disorder	X	X	X
History of ischemic stroke	Within 7 days	X		X
History of transient ischemic attack		X		X
History of intracranial hemorrhage		X	X	X
Indication for chronic oral anticoagulation		X	X
Prior administration of other P2Y12 receptor inhibitor		X		X