Figure 5.
OA-GL17d promoted TGF-β1 expression in HaCaT cells by inhibiting miR-663a expression. (a) Effects of OA-GL17d on miR-663a expression. (b) Effects of miR-663a mimic transfection on miR-663a expression in HaCaT cells. (c) Effects of miR-663a inhibitor transfection on miR-663a expression in HaCaT cells. (d) Effects of miR-663a mimic and inhibitor on TGF-β1 mRNA expression. (e) Effects of OA-GL17d on TGF-β1 mRNA expression. (f) Effects of OA-GL17d on TGF-β1 protein level. Data were obtained from three independent experiments; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 indicate significant differences between two groups. TGF-β1 transforming growth factor-β1