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. 2022 Jul 11;12:11770. doi: 10.1038/s41598-022-15967-0

Table 1.

The subjects' characteristics.

Males Females
Non-depressive symptoms Depressive symptoms P-value Non-depressive symptoms Depressive symptoms P-value
n 340 (81.3%) 78 (18.7%) 475 (79.6%) 122 (20.4%)
Age, yrs 55 (41, 67) 50.5 (38, 67)

0.179

0.228

56 (43, 66) 54 (37, 66)

0.179

0.373

 < 45 100 (29.4%) 31 (39.7%) 137 (28.8%) 43 (35.2%)
45 ≤ , < 65 136 (40.0%) 24 (30.8%) 202 (42.5%) 42 (34.4%)
65 ≤ , < 75 71 (20.9%) 18 (23.1%) 96 (20.2%) 27 (22.1%)
75 ≤  33 (9.7%) 5 (6.4%) 40 (8.4%) 10 (8.2%)
Height, cm 169.3 (164.4, 173.2) 168.9 (163.9, 173.7) 0.945 156.4 (151.9, 160.1) 155.5 (151.6, 160.6) 0.796
BW, kg 67.1 (60.9, 73.7) 65.4 (60.5, 73.0) 0.384 52.9 (48.1, 59.1) 53.2 (48.7, 57.5) 0.941
BMI, kg/m2 23.5 (21.6, 25.8) 23.4 (21.5, 25.2)

0.422

0.376

22.0 (19.8, 24.2) 22.0 (19.3, 24.7)

0.864

0.375

 < 18.5 9 (2.6%) 1 (1.3%) 51 (10.7%) 17 (13.9%)
18.5 ≤ , < 25 218 (64.1%) 57 (73.1%) 330 (69.5%) 76 (62.3%)
25 ≤ , < 30 95 (27.9%) 15 (19.2%) 75 (15.8%) 25 (20.5%)
30 ≤  18 (5.3%) 5 (6.4%) 19 (4.0%) 4 (3.3%)
CES-D 6 (2, 10) 19 (17, 24.8)  < 0.001* 7 (3, 10)
AST, U/L 23 (19, 29) 23 (19, 27) 0.768 20 (17, 24) 19 (16, 23)
ALT, U/L 21.5 (17, 31) 22 (18, 30) 0.683 16 (13, 20) 14.5 (11, 19)
BUN, mg/dL 14.7 (12.5, 17.8) 14.7 (11.9, 17.1) 0.395 13.5 (11.4, 16.1) 13.4 (11.0, 16.8)
Cre, mg/dL 0.83 (0.75, 0.92) 0.81 (0.74, 0.91) 0.563 0.61 (0.56, 0.67) 0.61 (0.55, 0.67)
BNP, pg/dL 6.2 (5.8, 11.1) 6.5 (5.8, 10.6) 0.754 9.4 (5.9, 15.1) 10.0 (6.0, 16.3)
HbA1c, % 5.6 (5.4, 5.8) 5.6 (5.3, 5.9) 0.353 5.8 (5.4, 5.8) 5.6 (5.3, 5.8)
Hypertension 106 (31.2%) 21 (26.9%) 0.498 115 (24.2%) 34 (27.9%)
DM 25 (7.4%) 6 (7.7%) 1.000 17 (3.6%) 3 (2.5%)
Dyslipidemia 42 (12.4%) 9 (11.5%) 1.000 56 (11.8%) 17 (13.9%)
CAD 8 (2.4%) 0 (0%) 0.361 7 (1.5%) 1 (0.8%)
Stroke 9 (2.6%) 1 (1.3%) 0.696 8 (1.7%) 3 (2.5%)
Current smoker 89 (26.2%) 19 (24.4%) 0.777 34 (7.2%) 13 (10.7%)
Alcohol drinker 245 (72.1%) 45 (57.7%) 0.020* 156 (32.8%) 37 (30.3%)

*P < 0.05. Differences between the non-depressive symptoms and depressive symptoms groups were examined by Fisher's exact test for categorical variables and Mann–Whitney test for continuous variables. Data are shown as number (a percentage of each group) or median (25 to 75th percentile).

ALT alanine transferase, AST aspartate transferase, BMI body mass index, BNP B-type natriuretic peptide, BUN blood urea nitrogen, BW body weight, CAD coronary artery disease, CES-D Center for Epidemiologic Studies Depression Scale, Cre creatinine, DM diabetes mellitus, HbA1c hemoglobin A1c.