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. 2022 Jul 12;60(6):750–761. doi: 10.1016/j.resinv.2022.06.007

Table 4.

Unadjusted and adjusted liner regression models for factors affecting the abnormal computed tomography findings in patients with COVID-19.

Unadjusted
Adjusted
Regression coefficient P-value Regression coefficient P-value
GGO (%)
 GSDMD, log pg/mL 13.12 [−0.52, 26.75] 0.059 8.22 [−4.92, 21.37] 0.213
 M30, U/L 0.0087 [−0.024, 0.041] 0.593 −0.00012 [−0.031, 0.029] 0.935
 Albumin, g/dL −4.99 [−11.12, 1.24] 0.113 −3.96 [−10.98, 3.06] 0.260
 LDH, U/L 0.0087 [−0.0053, 0.023] 0.219 0.0043 [−0.0084, 0.017] 0.498
Consolidation (%)
 GSDMD, log pg/mL 20.64 [11.25, 30.04] <0.001 18.32 [8.76, 27.87] <0.001
 M30, U/L 0.0082 [−0.018, 0.035] 0.529 −0.0083 [−0.030, 0.013] 0.443
 Albumin, g/dL −10.43 [−15.62, −5.24] <0.001 −8.88 [−13.99, −3.78] 0.001
 LDH, U/L 0.0049 [−0.0064, 0.016] 0.384 0.0018 [−0.0074, 0.011] 0.697
GGO plus consolidation (%)
 GSDMD, log pg/mL 33.76 [17.20, 50.32] <0.001 26.54 [10.01, 43.07] 0.002
 M30, U/L 0.017 [−0.028, 0.062] 0.446 −0.0095 [−0.047, 0.028] 0.610
 Albumin, g/dL −15.41 [−24.17, −6.66] <0.001 −12.84 [−21.67, −4.01] 0.006
 LDH, U/L 0.014 [−0.0055, 0.033] 0.159 0.0061 [−0.0099, 0.022] 0.446

β coefficient (presented as measured values with 95% confidence intervals) and P-values were calculated using a linear regression model. The final model was adjusted for GSDMD, M30, albumin, and LDH levels.

(GGO, ground glass opacity; GSDMD, gasdermin D; LDH, lactose dehydrogenase; M30, caspase-cleaved cytokeratin 18 fragment).