Table 2.
Summary of demographics and anchor variables at Baseline
| Parameter | ASPIRE I (n = 224) | ASPIRE II (n = 227) |
|---|---|---|
| Age, years | ||
| Mean (SD) | 39.3 (12.91) | 40.8 (13.07) |
| Range | 18–64 | 18–64 |
| Sex, n (%) | ||
| Women | 138 (61.6) | 136 (59.9) |
| Men | 86 (38.4) | 91 (40.1) |
| QLDS | ||
| Mean (SD) | 27.24 (6.40) | 26.77 (5.64) |
| Range | 0–34 | 5–34 |
| MADRS score | ||
| Mean (SD) | 41.1 (6.07) | 39.7 (5.48) |
| Range | 29–58 | 29–54 |
| CGI-SS-r, n (%) | ||
| Normal, not at all suicidal | 0 | 0 |
| Questionably suicidal | 8 (3.6) | 4 (1.8) |
| Mildly suicidal | 17 (7.6) | 16 (7.0) |
| Moderately suicidal | 57 (25.6) | 68 (30.0) |
| Markedly suicidal | 80 (35.9) | 90 (39.6) |
| Severely suicidal | 56 (25.1) | 45 (19.8) |
| Among the most extremely suicidal patients | 5 (2.2) | 4 (1.8) |
| CGI-SR-I, n (%) | ||
| No imminent suicide risk | 5 (2.2) | 3 (1.3) |
| Minimal imminent suicide risk | 12 (5.4) | 8 (3.5) |
| Mild imminent suicide risk | 17 (7.6) | 18 (7.9) |
| Moderate imminent suicide risk | 57 (25.6) | 63 (27.8) |
| Marked imminent suicide risk | 75 (33.6) | 80 (35.2) |
| Severely imminent suicide risk | 53 (23.8) | 49 (21.6) |
| Extreme imminent suicide risk | 4 (1.8) | 6 (2.6) |
| EQ-VAS | ||
| Mean (SD) | 42.0 (24.44) | 39.5 (22.62) |
| Range | 0–100 | 0–95 |
CGI-SR-I Clinical Global Impression of Imminent Suicide Risk, CGI-SS-r Clinical Global Impression of Severity of Suicidality-Revised, EQ-VAS EuroQol Visual Analog Scale, MADRS Montgomery–Åsberg Depression Rating Scale, QLDS Quality of Life Depression Scale, SD Standard Deviation