Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 28;14:914017. doi: 10.3389/fnagi.2022.914017

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Pun, Liu, Long, Leung, Leung, Mewborne, Gao, Shneyderman, Ozerov, Wang, Ren, Aliper, Bischof, Izumchenko, Guan, Zhang, Lu, Rothstein, Cudkowicz and Zhavoronkov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Network of dysregulated pathways in CNS comparisons. Each node represented a dysregulated pathway consisting of a set of genes. Nodes with similar gene contents (similarity coefficient > 0.35) were connected by edges, and the thickness of node-linking edges was proportional to the similarity between a pair of gene sets. Clusters of pathways were annotated based on the hierarchical level of pathways retrieved from the Reactome database. The constituent pathways of a cluster were colored in red or blue for activation or inactivation. Only clusters containing more than three pathways were shown.