Table 2.
Characteristics of the included external validation cohorts and clusters
| Dataset, cluster | No of patients | Start recruitment date | End recruitment date | Total No (%) of deaths | Mean (SD) age; (IQR) (years) | No (%) male |
|---|---|---|---|---|---|---|
| Karolinska Institute, Sweden | 1670 | 27 Feb 2020 | 1 Sep 2020 | 193 (11.56) | 57.30 (18.70); (43-71) | 983 (58.90) |
| Albert Einstein Hospital, Brazil | 453 | 27 Feb 2020 | 25 Jun 2020 | 17 (3.75) | 56.44 (14.92); (46-68.50) | 295 (65.05) |
| Czech Republic Academy of Sciences, Czech Republic | 213 | 3 Mar 2020 | 12 Oct 2020 | 42 (20)* | 68.56 (16.56); (58-80) | 105 (49) |
| University College London, UK | 411 | 1 Feb 2020 | 30 Apr 2020 | 115 (28) | 66 (53-79)† | 252 (61.31) |
| General Directorate of Epidemiology, Mexico: | ||||||
| All data, from this source | 28 176 | 1 Mar 2020 | 16 Apr 2020 | 12 990 (46.10) | 58.57 (15.93); (48-70) | 17 019 (60.40) |
| Development cohort excluded | 25 056 | 11 556 (46.12) | 59.08 (15.94); (49-70) | 15 035 (60.01) | ||
| Tongji Hospital,39 China | 332 | 10 Jan 2020 | 18 Feb 2020 | 155 (46.69) | 58.98 (16.65); (46-70) | 198 (59.64) |
| CAPACITY-COVID: | ||||||
| Belgium | 221 | 12 Feb 2020 | 14 Oct 2020 | 51 (23.08)* | 68.14 (15.72); (57-81) | 137 (61.99) |
| Egypt | 45 | 12 Apr 2020 | 12 Aug 2020 | 9 (20) | 60.89 (14.37); (50-73) | 21 (46.67) |
| France | 46 | 13 Feb 2020 | 18 Dec 2020 | 3 (6.52)* | 67.96 (12.52); (62-77) | 34 (73.91) |
| Iran | 90 | 10 Feb 2020 | 5 May 2020 | 13 (14.44)* | 63.19 (15.39); (53.25-73) | 59 (65.56) |
| Israel | 25 | 10 Apr 2020 | 9 Aug 2020 | 2 (8) | 50.36 (20.15); (31-67) | 14 (56) |
| Italy | 106 | 6 Feb 2020 | 4 May 2020 | 22 (20.75) | 70.72 (11.63); (62.25-78.75) | 72 (67.92) |
| Netherlands | 5100 | 22 Nov 2019 | 30 Jul 2020 | 1003 (19.67)* | 66.37 (14.15); (57-76) | 3172 (62.20) |
| Portugal | 44 | 25 Mar 2020 | 19 Aug 2020 | 10 (22.73)* | 71.43 (13.32); (63.75-82) | 30 (61.18) |
| Russia | 278 | 22 Apr 2020 | 4 Jun 2020 | 19 (6.83) | 60.09 (15.49); (50.25-71) | 137 (49.28) |
| Saudi Arabia | 389 | 29 Feb 2020 | 24 Sep 2020 | 57 (14.65)* | 50.56 (16.79); (38-62) | 270 (69.41) |
| Spain | 47 | 5 Mar 2020 | 20 Apr 2020 | 10 (21.28)* | 70.98 (16.68); (55-83.75) | 28 (59.57) |
| Jeroen Bosch Ziekenhuis, Netherlands | 383 | 9 Mar 2020 | 29 Dec 2020 | 154 (40.21) | 70.21 (14.79); (61-81) | 226 (59.01) |
| Iowa (USA), UnityPoint Hospitals: | ||||||
| Hospital 1 | 288 | 3 Mar 2020 | 31 Jul 2020 | 14 (4.86) | 46.49 (19.29); (32-59) | 147 (51.04) |
| Hospital 2 | 929 | 3 Mar 2020 | 31 Jul 2020 | 67 (7.21) | 50.12 (22.54); (33-68) | 454 (48.87) |
| Hospital 3 | 95 | 3 Mar 2020 | 31 Jul 2020 | 6 (6.32) | 45.31 (20.54); (27-59) | 45 (47.37) |
| Hospital 4 | 66 | 3 Mar 2020 | 31 Jul 2020 | 6 (9.09) | 48.77 (21.26); (31-65) | 39 (59.09) |
| Hospital 5 | 511 | 3 Mar 2020 | 31 Jul 2020 | 22 (4.31) | 51.03 (20.63); (35-67) | 240 (46.97) |
| Hospital 6 | 393 | 3 Mar 2020 | 31 Jul 2020 | 22 (5.60) | 45.35 (19.02); 30-60 | 176 (44.78) |
| Hospital 7 | 295 | 3 Mar 2020 | 31 Jul 2020 | 18 (6.10) | 47.60 (20.10); 32-63 | 162 (54.92) |
| Leicester covTrack, UK | 3908 | Jan 2020 | Apr 2021 | 110 (28.22) | 63.29 (19.19); (50-79) | 2063 (52.79) |
| King’s College Hospital, UK | 2400 | 28 Feb 2020 | 28 Mar 2021 | 295 (12.29) | 59.76 (20.58); (47-76) | 1314 (54.75) |
SD=standard deviation; IQR=interquartile range.
*
Observed number of deaths before multiple imputation.
†
Median (IQR).