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. 2022 Jun 28;12:880459. doi: 10.3389/fonc.2022.880459

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Copyright © 2022 Zhang, He, Lei, Mao, Yin, Zhong, Cao, Zheng and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Screening of DEFRGs between osteosarcoma and normal tissues. (A) Heatmap for 227 DEFRGs. DEFRGs with upregulation, downregulation, and no significant difference were indicated by red, blue, and white dots, respectively. (B) GO enrichment analysis of DEFRGs. (C) KEGG pathway enrichment analysis of DEFRGs. (D) Protein-protein interaction network of DEFRGs. DEFRGs, differentially expressed ferroptosis-related genes; GO, Gene Ontology; Kyoto Encyclopedia of Genes and Genomes.