Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 28;12:880459. doi: 10.3389/fonc.2022.880459

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhang, He, Lei, Mao, Yin, Zhong, Cao, Zheng and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Downregulation of RPARP-AS1 inhibited osteosarcoma cell growth migration, and invasion. (A) Survival analysis of osteosarcoma patients with high and low RPARP-AS1 expression. (B) RPARP-AS1 expression in osteosarcoma cell lines and osteoblast cell line. (C) Transfection efficiency of si-RPARA-AS1 in MNNG/HOS and U2OS cells. (D, E) CCK-8 (D) and colony formation (E) assays were utilized to detect the proliferative capacity of MNNG/HOS and U2OS cells after RPARP-AS1 downregulation. (F, G) Transwell assays were applied to determine the migration (F) and invasion (G) capacity of MNNG/HOS and U2OS cells after RPARP-AS1 downregulation (magnification, 100×). **p < 0.01.