Table 3. Weighted analysis of R0 resection and survival outcomes among preoperative CRT, CT, and surgery alone strategies.
Treatment type | R0 resection | 1-year OS | 3-year OS | 5-year OS |
---|---|---|---|---|
Preoperative (chemo)radiotherapy (n=1,026) | 80.2%; (95% CI: 79.8–80.6%); reference |
75.6%; (95% CI: 75.0–76.1%); reference |
46.4%; (95% CI: 45.7–47.1%); reference |
38.2%; (95% CI: 37.5–38.8%); reference |
Preoperative CT (n=5,027) | 63.9%; (95% CI: 63.6–64.2%); P<0.01 |
76.0%; (95% CI: 75.8–76.2%); P=0.47 |
46.2%; (95% CI: 45.9–46.4%); P=0.89 |
35.3%; (95% CI: 35.1–35.5%); P=0.09 |
Surgery alone (n=1,813) | 60.9%; (95% CI: 60.4–61.3%); P<0.01 |
63.3%; (95% CI: 62.9–63.7%); P<0.01 |
30.5%; (95% CI: 30.1–31.0%); P<0.01 |
23.3%; (95% CI: 22.9–23.7%); P<0.01 |
CRT, chemoradiotherapy; CRT, chemotherapy.