Figure 7.

Effect of folic acid (FA) pre-administration on emotional behaviors observed in female mice after ovarian radiation injury. (A) Heat map of the exploration trajectories representing the activity of mice in each group. Representative heat maps were selected from the mouse which was closest to the mean level for each group. Red boxes indicate center area. (B) Quantification of the total distance traveled for each group. (C) Quantification of center area exploration time for each group. (D) Representative track of elevated plus maze exploration for each group. (E) Time spent in the open arm of the elevated plus maze. (F) Entries into open arms of elevated plus maze. Error bars, standard error of mean (SEM). N = 8, ^*p < 0.05, ^**p < 0.01, and ^***p < 0.001.