Table 2.
Associations of baseline features with 1-year case fatality after MI in patients with type 1 diabetes
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age, years | <0.0001 | <0.0001 | ||
| <60 | Reference | Reference | ||
| 60–79 | 2.42 (1.95–3.01) | <0.0001 | 2.25 (1.78–2.84) | <0.0001 |
| ≥80 | 4.13 (3.09–5.53) | <0.0001 | 3.62 (2.59–5.05) | <0.0001 |
| Women | 0.90 (0.75–1.08) | 0.271 | 0.91 (0.74–1.10) | 0.325 |
| Comorbidities | ||||
| Alcohol abuse | 1.52 (1.08–2.13) | 0.017 | 1.50 (1.04–2.17) | 0.030 |
| Atrial fibrillation | 1.82 (1.46–2.27) | <0.0001 | 1.10 (0.87–1.40) | 0.435 |
| Cerebrovascular disease | 1.67 (1.37–2.04) | <0.0001 | 1.16 (0.94–1.43) | 0.158 |
| Chronic pulmonary disease | 1.53 (1.22–1.93) | 0.0003 | 1.25 (0.98–1.60) | 0.073 |
| Diabetic retinopathy or glaucoma | 0.76 (0.63–0.92) | 0.003 | 0.95 (0.77–1.17) | 0.625 |
| Diabetic hypoglycemic coma | 1.16 (0.90–1.50) | 0.256 | 1.18 (0.91–1.86) | 0.069 |
| Diabetic neuropathy | 1.00 (0.75–1.33) | 0.988 | 1.11 (0.82–1.49) | 0.495 |
| Diabetic ketoacidosis | 1.07 (0.78–1.46) | 0.688 | 1.35 (0.98–1.86) | 0.069 |
| Dementia | 2.09 (1.46–2.98) | <0.0001 | 1.33 (0.91–1.93) | 0.140 |
| Heart failure | 2.55 (2.13–3.05) | <0.0001 | 1.76 (1.44–2.16) | <0.0001 |
| Hypertension | 1.60 (1.27–2.01) | <0.0001 | 1.05 (0.82–1.36) | 0.684 |
| Liver disease | 2.39 (1.68–3.41) | <0.0001 | 2.10 (1.47–2.99) | <0.0001 |
| Malignancy | 1.38 (1.08–1.78) | 0.011 | 0.99 (0.76–1.29) | 0.924 |
| Paralysis | 1.01 (0.44–2.34) | 0.982 | 1.19 (0.51–2.77) | 0.684 |
| Peripheral vascular disease | 1.99 (1.67–2.38) | <0.0001 | 1.53 (1.25–1.86) | <0.0001 |
| Prior CABG | 0.95 (0.68–1.32) | 0.754 | 0.70 (0.50–0.98) | 0.040 |
| Prior MI | 1.52 (1.25–1.85) | <0.0001 | 1.11 (0.90–1.36) | 0.344 |
| Psychotic disorder | 0.80 (0.45–1.42) | 0.441 | 0.74 (0.39–1.41) | 0.361 |
| Rheumatic disease | 1.30 (0.96–1.77) | 0.092 | 1.15 (0.83–1.58) | 0.406 |
| Renal failure | 2.06 (1.72–2.46) | <0.0001 | 1.70 (1.38–2.08) | <0.0001 |
| Valvular disease | 1.55 (1.14–2.12) | 0.006 | 1.06 (0.77–1.46) | 0.712 |
| Revascularization | 0.39 (0.32–0.47) | <0.0001 | 0.59 (0.48–0.73) | <0.0001 |
| PCI | 0.42 (0.35–0.52) | <0.0001 | 0.57 (0.45–0.70) | <0.0001 |
| CABG | 0.65 (0.47–0.91) | 0.012 | 0.78 (0.55–1.11) | 0.172 |
| STEMI | 0.99 (0.82–1.21) | 0.932 | 1.80 (1.46–2.22) | <0.0001 |
| University hospital | 0.65 (0.54–0.78) | <0.0001 | 0.69 (0.57–0.84) | 0.0001 |
| Year of MI | 0.048 | 0.003 | ||
| 2005–2009 | Reference | Reference | ||
| 2010–2014 | 0.85 (0.68–1.05) | 0.127 | 0.77 (0.62–0.96) | 0.021 |
| 2015–2018 | 0.76 (0.61–0.95) | 0.015 | 0.66 (0.52–0.84) | 0.001 |