Table 2.

Abstinence rate at 6 months.

Groups and rate difference	CO-validated continuous abstinence (intention to treat)	CO-validated continuous abstinence (per protocol)
Control group, n/N (%)	51/271 (18.8)	51/128 (39.8)
Intervention group, n/N (%)	63/242 (26.0)	63/104 (60.6)
Rate difference (95% CI)	–7.2 (–14.4 to 0.0)	–20.7 (–33.4 to –8.1)
Odds ratio raw (95% CI)	1.5 (1.0 to 2.3)	2.3 (1.4 to 3.9)
P value	.05	<.001
Odds ratio adjusted (95% CI)a	1.52 (0.99 to 2.33)	2.35 (1.37 to 4.05)
P value	.05	.002

^aAdjusted by baseline CO-oximetry and bupropion intake.