Lack of dietary fiber derived-SCFA exacerbates the disturbed conduction in the atrium. (A) Left panel, representative immunofluorescent staining for connexin 43 (red) and N-cadherin (green) in the atrium of low-fiber, compared with control, high-fiber or low fiber+SCFA group. Right panel, co-localization ratios based on Pearson's correlation coefficients for connexin 43 and N-cadherin signals. ***, P<0.001; n=3 for each group; data are mean±SEM. (B) Representative western blot images (left panel) and related analyses (right panel) of atrial p-CaMKII, CaMKII, RyR2, and p-RyR2, with GAPDH or β-tubulin as an endogenous control. n=4-5; *, P<0.05; **, P<0.01; ***, P<0.001; data are mean±SEM; A.U., arbitrary units; student's t-test.