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. 2022 Jun 21;18(10):4071–4087. doi: 10.7150/ijbs.69495

Figure 1.

Figure 1

CENPU was significantly elevated in HCC and related to poor prognostication. (A) CENPU mRNA expression based on the TCGA-LIHC dataset. (B) qRT-PCR analyses of CENPU in 80 pairs of HCC samples. (C-D) CENPU protein expression in HCC clinical specimens was detected by immunoblotting and IHC analysis. (E-F) CENPU expression in hepatoma cell lines and immortalized human hepatocytes. (G-H) CENPU mRNA expression was correlated with HCC tumour grade and stage. (I) CENPU levels in metastatic and nonmetastatic HCC tissues based on GSE40467. (J) Kaplan-Meier analysis of OS and RFS in 80 HCC patients from Zhongnan Hospital. (K) Kaplan-Meier analysis of OS and RFS in 365 HCC patients according to the TCGA dataset. *p < 0.05; **p < 0.01; ***p < 0.001. T: tumour; NT: nontumor.